20 best medicines

20 best medicines.

*Review of the best in the opinion of the editors of expertology.. Aspects of the selection. This material is personal, not an advertisement and does not serve as buying advice. Before buying you need to consult with a specialist.

Rating of the best drugs.

Nomination place product name cost Review of medicines for sore throat, Bronchitis and cough one Flemoxin Solutab three hundred twenty six ₽ two Amoxiclav four hundred sixty six ₽ three Sumamed four hundred ₽ four Levofloxacin three hundred fifty nine ₽ five Suprax eight hundred eighteen ₽ Review of medications for maxillary sinusitis one Sultasin sixty four ₽ two Macropen three hundred thirty one ₽ three Rocephin five hundred one ₽ four Avelox three hundred thirty two ₽ five Isofra two hundred eighty three ₽ review of medicines for children one Cephalexin eighty nine ₽ two Clarithromycin four hundred forty two ₽ three Lincomycin hydrochloride one hundred fifty four ₽ four Roxythromycin one hundred forty seven ₽ five Fouradonin one hundred seventy seven ₽ Review of Broad-Range Drugs One Vilprafen Solutab seven hundred ₽ two Zinforo twenty eight three hundred two ₽ three Invanz one six hundred fifty ₽ four Cubicin five seven hundred forty seven ₽ five Maxipim one hundred ninety two ₽

A review of the best medicines for sore throat, bronchitis, and cough.

Inflammatory diseases of the upper respiratory tract are among the more common in medical practice. Children and adults are susceptible to such illnesses as sore throat and bronchitis. From time to time these pathological conditions can be caused by viruses, but often joined and bacterial infection. In this case, it is necessary to use bactericidal drugs (medicines). It should be recalled that antibiotic therapy should be carried out only after a complete examination of the patient, making a diagnosis and testing the sensitivity of the flora to a particular antibiotic.

Bacterial infection may be indicated by a rapid increase in body temperature, increasing signs of general intoxication (helplessness, head and muscle pain, dizziness), cough with purulent sputum. This article will review more affordable and effective drugs for sore throat, bronchitis, and cough in adults.

Flemoxin Solutab.

Popularity Rating*: 4.9.

The antibiotic Flemoxin Solutab (Amoxicillin) from the group of aminopenicillins, comes in the form of soluble pills of twenty pieces in a packet. There are several main dosages: 0.125г, 0.25г, 0.5 г, 1.0г. Amoxicillin is the main active ingredient that inhibits the growth and development of many gram-positive and gram-negative microbes (pus-like cocci, which in most cases provoke inflammatory diseases of the upper respiratory tract).

But this antibiotic got into the review because it is used not only for angina and bronchitis – it can also inhibit the growth of certain digestive microbes that provoke if – enteritis and inflammation in the urinary tract.

Advantages and disadvantages.

The main advantages of this drug are sharp and complete absorption in the gastrointestinal tract, a pleasant taste, the possibility of introduction from an early age of children. Another advantage of the product Flemoxin Solutab will be that it can be drunk both before and after a meal (and even during a meal). With proper use of this antibiotic, a pronounced therapeutic effect develops, starting from the first hours. But you can see it already after a few days.

The number of disadvantages include, first of all, frequent allergic reactions that occur after the introduction of the product, the high price (relative to analogues), and inability to inhibit the growth of microbes that produce an enzyme such as beta-lactamase (this enzyme destroys penicillins). In general, the advantages of Flemoxin even more, because this tool is often used in inflammatory processes that occur in the upper respiratory tract. Cost – two hundred rubles.

Amoxiclav.

Popularity Rating*: 4.8.

This is an antibiotic from the same group as Flemoxin Solutab – it belongs to the group of aminopenicillins. Amoxiclav (amoxicillin and clavulanic acid) is available in the form of pills of fourteen pieces in a pack. There are different doses of this antibiotic: 0.25г, 0.5г, 0.875g, but it should be noted that the amount of clavulanic acid remains constant at 0.125г. The cost of the antibiotic is three hundred and fifty rubles.

Advantages and disadvantages.

As mentioned above, in addition to the main active ingredient Amoxicillin, the product contains clavulanic acid, which plays an important role in the treatment of bronchitis and sore throat caused by microbes that synthesize beta-lactamase. Since this enzyme is capable of destroying penicillins, clavulanic acid overrides it, thus achieving a more pronounced and dramatic effect. Another advantage – the product does not have much effect on the functioning of the gastrointestinal tract.

The only disadvantage is that Amoxiclav, like all other penicillins, often causes allergic reactions (because before their intended use it is necessary to test for sensitivity). There can be a violation of the microflora of the intestinal tract and vagina (dysbacteriosis and dysbiosis), so Amoxiclav is always prescribed in conjunction with probiotics.

Sumamed.

Popularity Rating*: 4.8.

The antibiotic belongs to the group of macrolides, and is available as capsules, pills, suspension and lyophilisate for injection. The approximate cost is four hundred rubles. Sumamed (Azithromycin) inhibits intensively the production of bacterial cell wall proteins, which prevents the rapid reproduction of microbes. Sumamed is often used for treating acquired tonsillitis (sore throat) and lingering bronchitis. It is especially recommended for clients who, due to personal intolerance, cannot be treated with penicillin-based medications.

Advantages and disadvantages.

The advantage of Sumamed will be that it is a very active product that does not ask for infrequent use, and it is rightly included in the review. Has a good effect of accumulation in the organs and tissues of the body, a fairly long period of decay and semiejection, and will affect not only the aerobic bacteria (which develop in the presence of oxygen), and anaerobic (proliferating without oxygen access). Sumamed enables you to cure inflammatory processes of the upper respiratory tract if they are caused by chlamydia or mycoplasmas. The antibiotic is usually well tolerated (even in long courses), rarely causes hypersensitivity reactions. The disadvantage of this pharmaceutical product is its overhead.

Levofloxacin.

Popularity Rating*: 4.7.

The drug is available in the form of pills and solution for injection. Levofloxacin is a cheap, but quite effective product, the cost of which is one hundred rubles. The antibiotic belongs to the group of fluoroquinolones, first acts on the DNA of microbes, thus preventing them from multiplying. It is used in this case, if the patient has an allergic reaction to both penicillins and macrolides, which is not very often. Levofloxacin acts on a huge number of different microbes, this is exactly the reason for its high efficiency.

Advantages and disadvantages.

The main advantage, as mentioned above, is the wide range of action of this antibiotic, so it can be used in cases where angina or bronchitis are caused by several types of microbes (mixed infection). The antibiotic is rapidly absorbed and metabolized, acting simultaneously on the genetic apparatus of the microbes. Another indisputable advantage – low cost.

But the wide range of action is not only an advantage, but also a disadvantage of Levofloxacin. By killing pathogenic tiny organisms, the drug also destroys the body’s natural microflora. Therefore, it is possible to use this medication only in small courses and only under the supervision of a doctor. Otherwise it is highly probable that dysbacteriosis or fungal skin lesions and mucous membranes will develop. It is not uncommon for allergic reactions to develop against the background of Levofloxacin, so the drug is not recommended to prescribe at children’s age. Still, the antibiotic was included in the review as a representative of active and modern fluoroquinolones, and side effects are an inevitable consequence of any active product.

Suprax.

Popularity Rating*: 4.7.

The antibiotic belongs to the cephalosporin series and is available as capsules of 0.2 и 0.4г. Suprax (Cefixime) inhibits the reproduction of various types of microbes by inhibiting their division in the early stages. Use this medicine (like all other cephalosporins) for bronchitis and sore throat only if the tailor has a hypersensitivity reaction to all the above groups of drugs. Often Suprax is used for all-encompassing therapy of lingering bronchitis or tonsillitis caused by several types of microbes.

Advantages and disadvantages.

The main advantage is the effectiveness and speed of action of the antibiotic. It can be used even in children (Suprax is prescribed in this case, if the patient turned to the clinic late, and the infection is progressing and urgent help is needed). The antibiotic is rapidly absorbed and starts working, and its long half-life allows using it 1-2 times a day.

The drawbacks of Suprax are its high allergenicity, and the need for supportive therapy in the form of immunostimulants and probiotics, which focuses on the prevention of mycosis (fungal lesions) and dysbiosis. The cost is quite high and amounts to six hundred thirty rubles.

Review of the best drugs for maxillary sinusitis.

maxillary sinusitis is a disease that is an inflammation of the paranasal sinuses, which is accompanied by a rasping pain, fever and purulent nasal discharge. If you have these symptoms, you need to immediately contact a doctor to conduct the necessary research and diagnosis. Since maxillary sinusitis is almost always caused by microbes, medications are an indispensable part of the cure. But they are only used if the patient has a weakened immune system and the body can not cope with the infection without the help of others.

The need to introduce bactericidal medications for maxillary sinusitis is due to the fact that the infection from the sinuses may enter the skull cavity or spread haematogenously (through the blood vessels) to other organs. With untimely call in the healing institution is not only at risk of complications, and increases the possibility of transition to the acquired form of the disease, which is fraught with frequent inflammatory processes in the upper respiratory tract. This review is based on the preferences of the professional society of doctors.

Sultasin.

Popularity Rating*: 4.9.

An antibiotic from the protected aminopenicillin group that is available as a powder in vials (1.5г). It is diluted with saline or local anesthetic and injected into the body (intravenous or intramuscular).

The mechanism of action of protected aminopenicillins is that they bind to sensors on the surface of bacterial cells (no similar receptors in the body, so drugs in this group do not act on healthy cells and tissues). The aminopenicillins then inhibit the production of proteins that are part of the cell wall of microbes. In addition, Sultasin (Ampicillin and Sulbactam) acts on the enzyme penicillinase (beta-lactamase), which is produced by some strains of microbes and inhibits the activity of the main active substance. As a result, even resistant bacteria are killed by Sultasin.

Advantages and disadvantages.

The main advantages of this pharmaceutical product is the effectiveness and speed of action, and the antibiotic can also be used to heal maxillary sinusitis in children. Another advantage is the low cost, which is seventy rubles.

The disadvantages of protected aminopenicillins (including Sultasin) are the rapid elimination half-life (the product must be used frequently) and frequent allergic reactions. In addition, Sultasin affects the gastrointestinal tract and often causes dysbiosis.

Macropen.

Popularity Rating*: 4.8.

Macropen (Midekamycin) is an antibiotic from the macrolide class that has a bacteriostatic effect (intensely suppresses microbial growth over a long period of time). It is sold as a powder for oral administration, but the most common pills are 0.4g (16 units per pack).

Advantages and disadvantages.

Since the product has a bacteriostatic action, it can be used for maxillary sinusitis, prone to a prolonged or acquired course. Macropen is one of the more desirable pharmaceuticals if the patient has an allergic reaction to penicillins, (which is not uncommon), and this allowed it to get into the review. Macropen rarely causes any side effects and hypersensitivity reactions, when taking it even more rarely there is a dysbacteriosis of the intestinal tract. Another advantage – it is a long elimination half-life, so from time to time it is enough 1-2 pills per day. The product is suitable for treating mixed infections (caused by several types of microbes).

The disadvantages of pharmaceuticals include a fairly high price, which today is two hundred and twenty rubles. Macropen should not be used during pregnancy, breastfeeding and in early childhood (in such situations, it is used only in the latter cases).

Rocephin.

Popularity Rating*: 4.7.

Antibiotic from the group of cephalosporins has long been used to heal various inflammatory diseases, including maxillary sinusitis. The product has antibacterial action (destruction of germs), and for all that, it is active against even more pathogens than the penicillins and macrolides listed above. Rocephin (Ceftriaxone) is available in powder form in one g vials. Designed for intramuscular and intravenous administration, having previously dissolved the contents of the bottle in saline solution or local anesthetic.

Pros and cons.

As already mentioned, Rocephin can affect a huge number of different microbes. It has a long elimination half-life, so the patient does not need to worry about taking the drug every few hours – usually enough 1-2 injections per day. This fact allowed Rocephin to be included in the compliance review, in other words, by ease of administration, which leads to the highest adherence to healing.

The most important of the disadvantages is the fact that often intolerance to penicillins is combined with an allergy to cephalosporins, so it is always necessary to test before use. Another disadvantage is the fact that Rocephin does not inhibit beta-lactamase, which is synthesized by some bacteria as a protective enzyme. The cost of the product is quite high and is four hundred and fifty rubles. reme caution should be exercised when using Rocephin during pregnancy, breast feeding and early childhood. The therapy should be followed up to reduce the risk of dysbacteriosis and fungal infections.

Avelox.

Popularity Rating*: 4.6.

The antibiotic Avelox (Moxifloxacin) belongs to the fourth generation (most modern) fluoroquinolones, and this allows it to lead the review in this group. This group of drugs is 100% synthetic – similar substances are not found in the environment, but are made artificially. Avelox is available in the form of 0.4 g and a solution for injection.

Pros and cons.

The main advantage and the premise, why is quite often used Avelox in maxillary sinusitis unexplained etiology (origin) or mixed infection (including those caused by mycoplasmas and chlamydia), is explained by the fact that this drug has a wide range of action and can, in just a few days, to produce the desired therapeutic effect.

Flaws in Avelox are also quite. The drug is foreign to the body (as mentioned above, it is one hundred percent synthetic), so it is often possible to watch allergic reactions and dyspeptic phenomena (nausea, vomiting, diarrhea). In addition to gastrointestinal motility, Avelox affects the digestive flora – it suppresses it and leads to the development of dysbacteriosis, which is often joined by secondary infections (for example, fungal). The drug can not be used during pregnancy, from time to time it is used to heal maxillary sinusitis in children, but this requires severe indications. The cost of the antibiotic is six hundred rubles, which places it among quite expensive drugs.

Isofra.

Popularity Rating*: 4.5.

This is a topical antibiotic, which is available as a nasal spray in 15-ml bottles. Isofra (Framicetin) refers to aminoglycosides, which have a pronounced antibacterial effect. It is used intensively in medical practice for acute and acquired maxillary sinusitis caused by aerobic microbes (growing in oxygenated environment) and anaerobes (developing in anoxygen-free space). But in medical practice, the cure is applied only intranasally, because it is recognized to be quite poisonous compound (especially when it gets on the mucous membranes of the gastrointestinal tract).

Pros and cons.

The main advantage is a small course of healing, which is 3-7 days. But such a duration of therapy does not affect the effectiveness of Isofra. This remedy can be used both for healing adults and in the treatment of maxillary sinusitis that has appeared in childhood. For all that the antibiotic is practically not absorbed into the blood, so it has no effect on the liver, stomach and intestinal tract, does not cause immune system disorders and disbacteriosis, which allows the product to be given the highest place in the safety review.

The disadvantages of introducing Isofra include the fact that this product has no effect on pneumococci and streptococci, which are often the causative agents of prolonged maxillary sinusitis. Therefore, if the symptoms do not decrease after a week of implementation, another bactericidal product will have to be prescribed. The price of the drug is two hundred and fifty rubles.

Review of medicines for children.

At this point in the area of the Russian Federation, a huge number of medicines can be purchased without a prescription. People used to think that the bactericidal products that help almost any disease, but this is not true. Drugs are really effective only when the disease was provoked by microbes, but the viral origin of the pathology such pharmaceutical products can only worsen the condition of the baby, exactly as in the case of the disease caused by protozoa, for example, amebic dysentery.

Medications for children can be used only if they are prescribed by a doctor after all the necessary examinations. In all cases, the doctor must consider the personal characteristics of the body, the nature of the disease, as well as all existing indications and contraindications. It is better to prescribe bactericidal drugs that do not affect the motility of the intestinal tract and the normal flora of the body.

Cephalexin.

Popularity Rating*: 4.9.

An antibiotic from the group of beta-lactams, and specifically it refers to cephalosporins. Cephalexin is available in the form of capsules of 0.5g in sixteen packs. The product has a pronounced antibacterial action (destroys the smallest organisms). It is often used for inflammatory diseases of the upper respiratory tract, urinary system, skin and subcutaneous fat, ENT, musculoskeletal system. Its use can be from the newborn period, but the course and doses are chosen personally, taking into account the age and weight of the baby. This approval to use the product on newborns significantly increases the safety review of the product.

Advantages and disadvantages.

The advantage of Cephalexin is its low cost, which is currently sixty five rubles. It can be used from the first month of life of a baby, even for long and severe infections. With all this there is no need to take the product very often, 1-2 capsules a day is enough. Cephalexin has a strong effect on a wide range of microbes, inhibiting their reproduction. It may be used as a first-line product for pneumonia. It is one of the very few cephalosporins that are given in capsules rather than injectables.

The disadvantages may be possible side effects (dyspeptic phenomena: diarrhea, vomiting, nausea, flatulence) and allergic reactions. Caution should be exercised when treating prematurely born infants with a history of allergy.

Clarithromycin.

Popularity Rating*: 4.9.

Clarithromycin is a bactericidal drug that belongs to the macrolide series. This antibiotic has a mild bacteriostatic effect, so it is often used for long-term infections of the upper respiratory tract, rhinitis, otitis, sinusitis and maxillary sinusitis. It is available in the form of pills and capsules of 0.25 и 0.5г. Clarithromycin inhibits reproduction of festering bacteria, mycobacteria and Helicobacter infection, so it is often used for healing peptic ulcer disease.

Advantages and disadvantages.

The main advantage of Clarithromycin, as well as other bactericidal drugs from the macrolide group, is the low possibility of side effects. Therefore the product can be used in the first year of life of a baby. Another advantage is that it is enough to heal a course of six to ten days, with all this two capsules a day are prescribed. Rapid absorption and long half-life ensures effective action and a therapeutic effect within a short time. The cost of the antibiotic is average and is two hundred and thirty rubles.

Disadvantages of Clarithromycin can be named low activity in comparison with other antibiotics (for example, from the group of cephalosporins). Therefore, when ineffective or in the presence of mixed infection it is necessary to combine this drug with other bactericidal products. This may slightly reduce its effectiveness, but increases its safety.

Lincomycin hydrochloride.

Popularity Rating*: 4.8.

Lincomycin hydrochloride refers to drugs from the group of lincosamides. Can have both antibacterial and bacteriostatic effects on a huge variety of microbes. Lyricomycin hydrochloride is available as an injectable solution and in 0.25g capsules.25г. It is used in inflammatory processes of the skin, upper and lower respiratory tracts, bones and joints, heart and blood vessels. The product is rapidly absorbed from the gastrointestinal tract, and the maximum concentration is reached after a few hours. Intensely affects the coccus flora, bacilli and other types of microbes.

Advantages and disadvantages.

Prompt absorption and action of the product is an advantage, as well as probable bacteriostatic and antibacterial effects against many groups of microbes. The antibiotic is cheap, and can be purchased for fifty rubles today.

Lincomycin hydrochloride has disadvantages, and there are many of them. The antibiotic can only be used starting at age 6. It should be prescribed with caution if the patient has acquired digestive diseases, cardiomyopathies and allergic reactions. Lincomycin can lead to the development of dysbacteriosis and fungal infections of the skin and mucous membranes, so a supportive therapy is recommended. The cumulative balance of advantages and disadvantages allows lincomycin to hold a permanent, mid-range position in the review of drugs with a wide range of action.

Roxithromycin.

Popularity Rating*: 4.7.

This is an antibiotic from the macrolide group that is often used in pediatrics. Roxytromycin comes in the form of pills of 0.15g of ten pills in a packet. It belongs to the bactericidal product of wide activity range, therefore it has found an extensive practical application. It is used to heal inflammatory diseases of the skin, upper respiratory tract, urinary system, ENT organs, bones. Roxytromycin is also used in the treatment of children’s infections caused by microbes, namely: scarlet fever, whooping cough, diphtheria. It is often used to prevent infectious myocarditis during dental interventions.

Advantages and disadvantages.

Rating advantage is the mild bacteriostatic action, which extends mainly only to the smallest pathogenic organisms. With all this, the normal intestinal tract microflora is not actually tormented, so dysbacteriosis and associated fungal infections – this is unique. Virtually never Roxytromycin does not cause allergic reactions. The drug is rapidly absorbed from the gastrointestinal tract and does not require frequent dosing. The cost of the antibiotic is quite low and is one hundred forty rubles.

Among the disadvantages of Roxithromycin we can highlight the negative impact on the liver enzymatic activity, so the antibiotic should not be prescribed if the function of this gland is impaired. It is not recommended to prescribe toddlers under two months of age.

Furadonin.

Popularity Rating*: 4.6.

Furadonin (Nitrofurantoin) is a drug with pronounced antimicrobial activity, which belongs to the class of nitrofuran derivatives. Intensely inhibits the reproduction of microbes by inhibiting the synthesis of RNA and DNA. Furadonin is more widely used in urology. Thanks to its bacteriostatic action, it is used even for long-term urinary tract infections (pyelonephritis, cystitis, urethritis). Available in the form of pills to be taken 2-3 times a day (on the advice of the doctor).

Advantages and disadvantages.

The main advantage of Furadonin is that urinary tract pathogens do not actually develop resistance (resistance) to this product, which increases the effectiveness of long-term use. Therefore it can be taken as part of an all-encompassing cure, which includes several courses. It is rapidly absorbed in the stomach, penetrates into the blood plasma and binds with proteins, and then starts acting on the nephrons in the kidneys. The cost of the antibiotic is low, amounting to seventy five rubles.

The disadvantage can be named the fact that Furadonin can be used only from the age of twelve, earlier – on evidence and with caution. But in this case, it is completely replaceable by furagin. The product can affect the function of the liver and the gastrointestinal tract as a whole, occasionally causing allergic reactions, neurotic disorders and the phenomena of dyspepsia.

An overview of the best medications for a wide range of effects.

Many inflammatory diseases are caused by microbes, so the destination of drugs in this case is the main measure of etiotropic treatment (aimed at the cause of the disease). For more effective bactericidal product is necessary to take the material tailor and do culture, and then find the sensitivity of microbes to these or other drugs. But such an analysis may be done from a few days to a few weeks, and the patient occasionally need bactericidal therapy at the time of appealing for medical help.

A wide variety of medications are used for this purpose. Their essence is that they can act on a huge number of varieties of microbes and inhibit their growth. Let’s look at an overview of the more popular drugs.

Wilpafen Solutab.

Popularity Rating*: 4.9.

It is a bactericidal product that belongs to the latest generation of the macrolide group. Available as dispersed pills of ten in a 1g dose packet. Vilprafen Solutab (Josamycin) in small doses suppresses the reproduction of microbes, in other words it has a bacteriostatic effect. But in large doses it acts as a regular antibacterial agent (kills the smallest organisms). It is used to treat many diseases: infections of the upper and lower respiratory tracts, genitourinary system, ENT organs, skin, and is occasionally used for gastritis, which is caused by the action of Helicobacter pylori.

Pros and cons.

The advantage SCHEISSDRECK from German to English of this pharmaceutical product will be that it actually has no effect on the microflora of the intestinal tract, does not cause dysbacteriosis. It has a long effect due to the long period of semiejection. It is rapidly absorbed by the gastrointestinal tract, and the maximum concentration is reached in the blood in an hour. Indicated for the treatment of many infections.

The disadvantage is the fact that Vilprafen Solutab leaks through the placenta and can be excreted with milk during the period when lactation takes place. The antibiotic has a fairly high cost, which is currently six hundred thirty rubles.

Zinforo.

Popularity Rating*: 4.9.

Zinforo (Cefarolina fosamil) is the 5th, latest generation antibiotic of the cephalosporin series, which has antibacterial action. The antibiotic inhibits (suppresses) the growth of both Gram-negative and Gram-positive microbes. Affects the smallest organisms that reproduce in oxygen and oxygen-free environments (aerobes and anaerobes). It can be used for certain inflammatory processes caused by microbes, namely, skin diseases, and diseases of the upper and lower respiratory tracts.

Quite rapidly absorbed, slowly excreted. Does not affect erythrocytes and hematopoiesis, gastrointestinal tract can be quite strong (suppresses normal microflora). It is available in powder form of 0.Diluted with physiological material before administering it.

Advantages and disadvantages.

The advantage of the product is its high efficiency: usually, only a few injections are enough to achieve the therapeutic effect. It can be used for inflammatory diseases, when the phenomena of mixed infection (caused by several infections) are observed.

But the antibiotic can affect the gastrointestinal tract, disrupting the main functions of the liver. The drug has a higher cost, Zinforo is not sold in all pharmacies, from time to time it is quite difficult to buy. It should be used with caution during pregnancy, lactation, and childhood. Like all cephalosporin drugs, this product does not have a tablet or capsule form – it is used exclusively as an injection. This fact can also quite “lower the rating” of the product, despite its modernity and high efficiency.

Invanz.

Popularity Rating*: 4.8.

Invanz (Ertapenem) is a bactericidal product from the group of carbapenems, which belongs to the latest generation of drugs with a wide range of action. Available as lyophilisate for injection in twenty ml, with one vial containing one g of active substance. It is used for peritonitis, contagious complications of abortion, pneumonia and other inflammatory respiratory diseases. Invanz is often prescribed for purulent inflammations of the skin and subcutaneous fatty tissue, meningitis, encephalitis and sepsis. Invanz has a strong antibacterial effect against many microbes.

Advantages and disadvantages.

Invanz is rapidly absorbed and begins to act on the smallest organisms – it is administered intramuscularly or intravenously. Often has a strong and rapid action, even in severe bacterial infections (septicemia, prolonged pyelonephritis). Can act on Gram-positive and Gram-negative aerobic and anaerobic bacilli and cocci. This antibiotic by right takes the highest position in the review – because it has changed such strong drugs as Thienam and Meronem, and occasionally languishing clients can only “rely” on such funds.

The disadvantages of this antibiotic can be called frequent side effects that occur during the implementation of the pharmaceutical agent. In 2-3% of cases it causes dyspeptic complaints (nausea, vomiting, diarrhea), sometimes it affects the central nervous system, provoking migraine, dizziness, vision and hearing disorders. The effects of Invanz on the intrauterine development of the fetus have not been assessed; therefore, it should only be used during pregnancy when the benefits exceed the probable adverse effects. The cost of the product is high and amounts to one thousand seven hundred rubles.

Cubicin.

Popularity Rating*: 4.8.

Kubicin (Daptomycin) is available as lyophilizate for injection at 0.35 or 0.5 g in vial. This antibiotic belongs to the latest generation of lipopeptides (repeats). Affects Gram-positive bacterial flora to a greater extent and Gram-negative bacteria to a lesser extent. Often used for infections that are caused by antibiotic-resistant Staphylococcus aureus. Appointed, for example, in inflammatory processes of the skin and subcutaneous fatty tissue, postoperative purulent complications (including myocarditis and endocarditis), sepsis.

Advantages and disadvantages.

The main advantage of Kubitsin is its pronounced antibacterial effect, which develops on 2-3 days after the start of therapy. With all this, a sufficient therapeutic effect is achieved immediately, and in the future it is maintained by administering additional doses of the product. Side effects caused by the antibiotic are rare.

Therefore, the product is indicated for septic conditions, because in the presence of a high concentration of pathogens in the blood can not be used antibacterial drugs: the destruction of a large number of bacteria in the blood will lead to the release of their antigens and causes of pathogenicity in the blood, which can cause infectious – toxic shock. That’s why the bacteriostatic action of Kubitsin allowed it to get a place in the safety review.

The disadvantages can be considered the fact that Kubitsin must be taken for 10-14 days. As a result of active suppression of the body’s normal microflora, aggravations such as fungal skin and urinary tract infections, migraines and neurotic disorders can develop. The cost is the highest and amounts to four thousand nine hundred rubles. It is not recommended to use under the age of eighteen years, during pregnancy, lactation, and after sixty-five years, especially if there are acquired gastrointestinal diseases, including liver.

Maxipim.

Popularity Rating*: 4.7.

Maxipim (Cefipim) is a four-generation antibiotic from the group of cephalosporins. It is available in powder form in 1g and 0.5г. Before intravenous or intramuscular injection, it should be dissolved in saline solution or local anesthetics. The product has a strong antibacterial action, reaching peak concentrations in plasma after 2-3 days. The half-life and half-removal period is long, so it is enough to administer 1-2 injections a day. Maxipim is used for treatment of bacterial infections of the upper respiratory tract, urinary system, genital organs, skin and generalized processes (septicemia, septicaemia).

Advantages and disadvantages.

The advantages of Maxipim are its high speed of action, as well as the fact that it is not necessary to make injections more than twice a day. At the same time, Maxipim affects a large number of different microbes that often cause hospital and out-of-hospital infections. The antibiotic can be used in children, but it should be done with caution and only under the supervision of a doctor. Another plus – it’s low cost, which is three hundred and twenty rubles.

The disadvantages can be named the negative effect on the microflora of the intestinal tract. That is why it is always necessary to prescribe additional therapy, which is aimed at reducing the risk of dysbacteriosis development. Maxipim is not recommended for use during pregnancy. As with other cephalosporins, the popularity rating may be lowered by the lack of oral forms (in the form of pills and capsules for intravenous injection).